for us to be taken seriously—not just within our society but beyond as well.”
NIH funding and support opens doors beyond research, Dr. Vedantham said. After receiving funding for ATTRACT, he was invited to participate in multiple government panels and large- scale initiatives within the broader medical community.
“The seat at the table came largely from the perception that there is a rigorous partner in IR,” he said. “I think Dr. Sista will experience the same thing. IR has longed to have an even larger footprint in the oversight and regulation of medicine, and one of the best and most effective ways is to be established as a credible and involved partner in care.”
How to join PE-TRACT, and its potential impact, is a celebration of the field of IR, according to Dr. Sista—one he hopes other IRs will encourage and support.
Participating in PE-TRACT will be ideal for those interested in becoming involved in clinical research, have a passion for PE and want to develop a reputation in their community as a high-minded researcher.
producing data to prove the value of our interventions.” A secondary benefit of the trial, Dr. Vedantham said, is proving to the NIH that IR can contribute rigorous researchers to the broader scientific community.
Dr. Sista also cites these benefits as a key outcome of the study.
“Not only can PE-TRACT put IR on the map as a serious specialty that cares about science and finding the truth, but we can hopefully also empower future IRs to undertake such questions and use the model and mentorship of Suresh and other IR leaders to conduct trials like ATTRACT, C-TRACT and PE-TRACT,” Dr. Sista said. “We want to encourage young and hungry investigators to research genicular artery embolization or prostate artery embolization or some of the other major interventions that IRs are known for, to really raise the bar for the type of evidence that needs to be generated
16 IRQ | FALL 2022
Dr. Sista is actively looking for sites to enroll into PE-TRACT. Site investigators must believe in the questions being asked, be comfortable with randomization and have the facilities and resources for cardiopulmonary exercise testing. According to Dr. Sista, participating in PE-TRACT will be ideal for those interested in becoming involved in clinical research, have a passion for PE and want to develop a reputation in their community as a high- minded researcher. Dr. Sista hopes to have 40–50 sites enrolled by mid-2023, with enrollment completed within 3–4 years and data published by 2028–2029.
“There are very few investigator-initiated studies in the environment of PE care right now. So we need to champion this, celebrate it, prioritize it and ensure its success,” he said. “Not only because its success will cement IR’s place in high- minded research, but because it will also cement the idea that we can conduct NIH research and do so successfully.”
For more information or to enroll your site in PE-TRACT,
IRs are encouraged to email Dr. Sista at
asista@gmail.com.
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