PE-TRACT trial Purpose: To compare the treatment of pulmonary embolism using either catheter-directed therapy or anticoagulant alone to determine best efficacy, safety and long-term outcomes.
The Pulmonary Embolism: Thrombus Removal with Adjunctive Catheter- directed Therapy (PE-TRACT) study will assess the efficacy and long-term impact of CDT plus anticoagulation on intermediate-risk PEs over anticoagulation alone. PE-TRACT is an NIH-funded, multicenter trial seeking to enroll up to 500 patients. The resulting data will not only examine the impact of CDT but also provide deeper insight into the biology of PEs.
“The first end goal is to give Level 1 data to the PE community to help them make decisions when they’re confronted with an acute PE patient who’s presenting with an immediate-risk PE,” said principal investigator Akhilesh Sista, MD, FSIR. “The second goal of PE-TRACT is to really understand the natural history of PE through a rigorous trial and see if something we as IRs do relatively frequently can improve quality of life and functional capacity and exercise tolerance in the year following PE.”
Dr. Sista is actively looking for sites to enroll into PE-TRACT, with the aim of publishing data by 2028–2029. According to Dr. Sista, participating in PE-TRACT will be ideal for those interested in becoming involved in clinical research, have a passion for PE and want to develop a reputation in their community as a high-minded researcher.
“There are very few investigator-initiated studies in the environment of PE care right now. So, we need to champion this, celebrate it, prioritize it and ensure its success,” he said. “Not only because its success will cement IR’s place in high- minded research, but because it will also cement the idea that we can conduct NIH research and do so successfully.”
READ MORE Racine H, Kirby J. Building an NIH-funded trial: Inside the origin and design of PE-TRACT. IR Quarterly. Fall 2022.
1994
Research RESOURCES
The future of IR rests in high-quality, evidence-based care. SIR's scholarly journal, in concert with SIR Foundation, ensure the development and access of evidence-based research.
The Journal of Vascular and Interventional Radiology: Consistently voted a top member benefit, JVIR provides peer-reviewed, evidence-based research free to SIR members.
• JVIR translated: To expand its access to the international IR community, JVIR launched JVIR IberoAmerica, which translates the abstracts of each issue into Spanish and Portugeuse, and JVIR China, which translates the abstracts into Chinese.
• Visual abstracts: Since 2021, JVIR has provided graphical abstracts of select articles. These visual abstracts offer an accessible and interactive way to engage in JVIR’s featured science.
• JVIR Access: Also known as the JVIR blog, this site offers article summaries and commentaries on current and past articles.
SIR Foundation: The Cardiovascular and Interventional Radiology Research Education Foundation (CIRREF) was established in 1989. Today, we know it as SIR Foundation. Over the years, SIR Foundation has funded grants, identified research needs and promoted evidence-based care.
• Scientific funding: Between 1996 and 2022, SIR Foundation has awarded 282 total research grants totaling $5,907,380. In 2013 alone, SIR Foundation awarded $198,264 across 15 grants, which resulted in 14 scholarly publications.
• Research Consensus Panels: SIR Foundation has hosted 42 RCPs and Summits on various topics since 2002, bringing together a panel of experts to identify research gaps and priorities in different areas. Out of the 42 panels, 33 have been published in JVIR (78%), with more in progress. Fourteen of these panels have gone on to apply for funding via the SIR Foundation Incubator Grant, and 10 were awarded.
• Return on investment: SIR Foundation-supported research has gone on to receive $68 million in funding by the National Institutes of Health—an 8 to 1 return on investment.
• The growth of scientist members: In 2022, SIR Foundation added the Scientist position to the board to help identify research areas and identify opportunities to support PhD SIR members. This led to the creation of the Non-Clinical Scientist Committee and the Research Scientist Award. Since the creation of this position, SIR has grown from 19 Scientist members to 45.
1995 Subspecialty recognition
Vascular and interventional radiology (VIR) is recognized by American Board of Medical Specialties (ABMS) as a subspecialty of diagnostic radiology.
irq.sirweb.org | 17 1996 1997
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