hile there may be orms o olate or olic acid that may help better delier anti-cancer aents,24


people ould be better o not intentionally takin olic acid in supplements.


Conclusion


Folate oer-supplementation and deciency causes pro- phase DNA damae.25


but oer-supplementation ith olic acid can be a problem.


aura Bell correctly stated, e all need the natural olate ound in leay reens, orane uice, and other oods, and diets hih in these oods are perectly healthy many researchers, thouh, beliee that olic acid may be both riend and oe. hen cells in the body are healthy, olate helps shepherd alon the normal replication o DNA. But hen cells are malinant or in daner o becomin so  and as many as hal o adults older than 60 could already hae precancerous colon polyps, hile most middle-aed men hae precancerous cells in their prostates  animal studies suest excess olate in the orm o olic acid may act like as on the re loerin your intake to 400 mc on’t hurt  and miht help sae your lie.14


t is clear that since olic acid is unnatural, synthetic, chemically dierent, structurally dierent, and is not absorbed in the same pathays as olate, lon-term olic acid consumption may be haardous to human health. Folate in oods is hat is sae and is the preerred orm o olate or human consumption. Excessie olic acid may make cancer orse. And unlike olic acid, humans hae been saely consumin ood olate or thousands o years.


is becomin more eident that those arnins should hae been heeded by more people. Eeryone should be concerned about takin syntheticisolated SP itamins like those containin olic acid. And i olate is needed, it should be taken in one o its hihly benecial ood orms.


About the Author Dr. Thiel, Ph.D. is a nutrition scientist and president o Doctors’ Research, nc. .doctorsresearch.com. e also runs a holistic health clinic in roer Beach, Caliornia .healthresearch.com.


References 1. Carmel R. Folic Acid. n Modern Nutrition in ealth and Disease, 10th ed. ippincott illiams  ilkins, Philadelphia, 2006: 47-481


4. Alala seeds, sprouted ra. SDA National Nutrient Database or Standard Reerence, Release 16-1, 2004


3. Broccoli, ra. SDA National Nutrient Database or Standard Reerence, Release 18 (2005)


7. Baano A, Reynolds K, older KN, e . Eect o olic acid supplementation on risk o cardioascular


6. hitney EN, amilton EMN. nderstandin Nutrition, 4th ed. est Publishin, N, 1987


THE ORIGINAL INTERNIST NE 2016


Some hae been arnin people aainst possible olic acid daners or many years.2, 8,13,26,27


No perhaps it So obiously humans need olate,


it seems that many


8. ucock M. s olic acid the ultimate unctional ood component or disease preention BM, 2004328:211- 214


diseases: a meta-analysis o randomied controlled trials. AMA. 2006296(22):2720-2726


9. onale-ross M, Marcos A, Pietrik K. Nutrition and conitie impairment in the elderly. 200186:313-321


Br  Nutr


10. Verhoe P. omocysteine metabolism and risk o myocardial inarction: Relation ith itamin B6, B12, and Folate. Am  Epidemiol 1996143(9):845-859 Vitamins as homocysteine-loerin


11. Brattstrom .


13. Thiel R. Natural itamins may be superior to synthetic ones. Med ypo, 200055(6):461-469


12. Carmel R. Folic Acid. n Modern Nutrition in ealth and Disease, 10th ed. ippincott illiams  ilkins, Baltimore, 2006:470-481


15. Fiueiredo C, rau MV, aile R, Sandler RS, Summers R, Bresalier RS, Burke CA, McKeon- Eyssen E, Baron A. Folic acid and risk o prostate cancer: results rom a randomied clinical trial.  Natl Cancer nst. 2009 Mar 18101(6):432-5


id35874922nshealth-diet_and_nutrition http:.msnbc.msn.com


14. Bell . s your breakast iin you cancer Research links too much olic acid to certain cancers. Preention. March. 29, 2010.


aents: A mini reie. Presentation at The Experimental Bioloy 1995 AN Collouium, April 13, 1995, Atlanta eoria


17. de Balle , et al. Dietary olate intake and breast cancer risk: European prospectie inestiation into cancer and nutrition.  Natl Cancer nst. 2014 Dec 12107(1):367


18. noue-Choi M, reenlee , Oppeneer S, Robien K. The association beteen postdianosis dietary supplement use and total mortality diers by diet uality amon older emale cancer suriors. Cancer Epidemiol Biomarkers Pre. 2014 May23(5):865-75


21. rupp S, reenber M, Ray , Busto , anctt K, Nulman , Koren . Pediatric cancer rates ater uniersal olic acid our ortication in Ontario.  Clin Pharmacol. 2010 May 10


23. Stobbe M. A Study Asks: Too Much Folic Acid a Cause o Autism ABC Nes, May 11, 2016


2. Shils ME, Olson A, Shike M. Modern Nutrition in ealth and Disease, 9th ed. illiams  ilkins, Balt., 1999


5. endler SS, Rorik D, eds. PDR or Nutritional Supplements. Medical Economics, Montale (N), 2001


25. Ortbauer M, Ripper D, Fuhrmann T, assi M, Auerni- aselmaier S, Stieler C, Kni . Folate deciency and oer-supplementation causes impaired olate metabolism: Reulation and adaptation mechanisms in Caenorhabditis eleans. Mol Nutr Food Res. 2016 Apr60(4):949-56


24. i , u , Piao , u , an , Kondadasula SV, Carson E, ee R. Folate-immunolobulin  as an anticancer therapeutic antibody. Bioconu Chem. 2010 May 1921(5):961-8


26. Thiel R. s Folic Acid aardous to our ealth The Oriinal nternist, 200411(2):39-40


61


27. Thiel R. Folic Acid is aardous to our ealth. The Oriinal nternist, 201017(2):88-90 


20. Mursu ., et al. Dietary Supplements and Mortality Rate in Older omen: The oa omen’s ealth Study. Arch ntern Med. 2011171(18):1625-1633


19. Castillo- C1, Tur A, auy R. Folate and breast cancer risk: a systematic reie oriinal article in Spanish Re Med Chil. 2012 Feb140(2):251-60


22. yer R, Tomar SK. Folate: a unctional ood constituent.  Food Sci. 2009 No-Dec74(9):R114-22


16. Steens V, McCullouh M, Sun , apstur SM. Folate and other one-carbon metabolism-related nutrients and risk o postmenopausal breast cancer in the Cancer Preention Study  Nutrition Cohort. Am  Clin Nutr. 2010 un91(6):1708-15


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