moderate activity against Staphylococcus aureus and Haemophilus influenzae (Herath et al., 2012). H. influenzae remains a significant cause of otitis media and pediatric respiratory infections, though vaccination has dramatically reduced incidence in young children (Shooraj et al., 2019). Epicorazines A and B also inhibit


Pythium species (Brown et al., 1987), important pathogens in forestry and agriculture. Pythium insidiosum, a related oomycete, causes vision- threatening keratitis and responds better to antibiotics than antifungals (Gurnani et al., 2022). Liquid cultures of Podaxis have


yielded podaxisterol, absent from wild fruiting bodies, with mild antibacterial activity in several derivatives (Guo et al., 2022). Enzymes from Podaxis show potential applications in paper manufacturing, food and beverage processing, detergents, bioremediation, wastewater treatment, and cancer radiotherapy (Sai et al., 2023). Finally, Podaxis also appears in


homeopathic practice for menstrual complaints, prolapsed uterus, irregular cycles, menorrhagia, ovaritis, and menopausal symptoms.


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